Article
Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique - 1 Jan 2013
Madadi Parvaz, Amstutz Ursula, Rieder Michael, Ito Shinya, Fung Vincent, Hwang Soomi, Turgeon Jacques, Michaud Veronique, Koren Gideon, Carleton Bruce C
Abstract excerpt
This guideline is intended to provide a basis for informed decision-making regarding genetic testing to identify those individuals who will not benefit from codeine therapy, as well as those who are at an increased risk for codeine-induced toxicity. This guideline addresses the following key questions: 1) Should genetic testing for CYP2D6 be performed in patients prior to the initiation of codeine therapy? 2) How...
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