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Article

CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans.

Infection and immunity - 1 Mar 2015

Break Timothy J, Jaeger Martin, Solis Norma V, Filler Scott G, Rodriguez Carlos A, Lim Jean K, Lee Chyi-Chia Richard, Sobel Jack D, Netea Mihai G, Lionakis Michail S

Abstract excerpt

Candida albicans is part of the normal commensal microbiota of mucosal surfaces in a large percentage of the human population. However, perturbations of the host's immune response or bacterial microbiota have been shown to predispose individuals to the development of opportunistic Candida infections. It was recently discovered that a defect in the chemokine receptor CX3CR1 increases susceptibility of mice and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25547797
DOI: 10.1128/IAI.02604-14
PMCID: PMC4333470

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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