Article
Insights from human studies into the host defense against candidiasis.
Cytokine - 1 Apr 2012
Filler Scott G
Abstract excerpt
Candida spp. are the most common cause of mucosal and disseminated fungal infections in humans. Studies using mutant strains of mice have provided initial information about the roles of dectin-1, CARD9, and Th17 cytokines in the host defense against candidiasis. Recent technological advances have resulted in the identification of mutations in specific genes that predispose humans to develop candidal infection....
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