Article
IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.
PLoS pathogens - 1 Jan 2013
De Luca Antonella, Carvalho Agostinho, Cunha Cristina, Iannitti Rossana G, Pitzurra Lucia, Giovannini Gloria, Mencacci Antonella, Bartolommei Lorenzo, Moretti Silvia, Massi-Benedetti Cristina, Fuchs Dietmar, De Bernardis Flavia, Puccetti Paolo, Romani Luigina
Abstract excerpt
The ability to tolerate Candida albicans, a human commensal of the gastrointestinal tract and vagina, implicates that host defense mechanisms of resistance and tolerance cooperate to limit fungal burden and inflammation at the different body sites. We evaluated resistance and tolerance to the fun...
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