Modulating Host Signaling Pathways to Promote Resistance to Infection by Candida albicans

Abstract excerpt

Candida albicans is a common human fungal pathogen that can cause systemic infections in healthy as well as immune compromised patients. Current therapeutic approaches have limited effectiveness, especially once a serious infection is established, in part due to the immune response. Although an efficient inflammatory response is necessary to fight infection, the typical response to C. albicans results in...

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