Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-redundant role of the chemokine receptor CX3CR1 in the anti-inflammatory function of gut macrophages.

Immunobiology - 1 Feb 2017

Marelli G, Belgiovine C, Mantovani A, Erreni M, Allavena P

Abstract excerpt

Mucosal immunity at the intestinal level is constantly challenged by the presence of external food and microbial antigens and must be kept under strict control to avoid the rise of aberrant inflammation. Among cells of the innate immunity, macrophages expressing the chemokine receptor CX3CR1 are strategically located near the gut epithelial barrier. These cells contribute to the maintenance of homeostasis by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colitis
Share to CX3C Chemokine Receptor 1
Share to Immunophenotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation Mediators

Share to Intestinal Mucosa

Share to Intestines

Share to Leukocytes

Share to Macrophages

Source

Identifiers

PMID: 27707514
DOI: 10.1016/j.imbio.2016.07.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-redundant role of the chemokine receptor CX3CR1 in the anti-inflammatory function of gut macrophages.PMID 27707514Read ↗

In vivo depletion and genetic targeting of mouse intestinal CX3CR1(+) mononuclear phagocytes.Semantic proximity Read ↗

Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis.Semantic proximity Read ↗

Lysophosphatidic acid-mediated GPR35 signaling in CX3CR1 <sup>+</sup> macrophages regulates the intestinal cytokine milieuSemantic proximity Read ↗

Investigating the orchestration of the inflammatory response : a role for chemokine receptors CCR1, CCR2, CCR3 and CCR5Semantic proximity Read ↗

Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.Semantic proximity Read ↗

Ginsenoside Rg1 Ameliorated Colitis by Regulating the Homeostasis of M1/M2 Macrophage Polarization and Intestinal FloraSemantic proximity Read ↗

CX3CR1⁺ cells facilitate the activation of CD4 T cells in the colonic lamina propria during antigen-driven colitis.Semantic proximity Read ↗

Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation.Semantic proximity Read ↗

Interleukin-17 induces an atypical M2-like macrophage subpopulation that regulates intestinal inflammation.Semantic proximity Read ↗

Hydroxychloroquine ameliorates DSS-induced colitis by inhibiting M1 macrophage polarization through NF-κB/NLRP3 signaling pathwaySemantic proximity Read ↗

Chemokine Receptors and Phagocyte Biology in ZebrafishSemantic proximity Read ↗

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.