Article
A second Candida albicans resistance gene (Carg2) regulates tissue damage, but not fungal clearance, in sub-lethal murine systemic infection.
Microbial pathogenesis - 1 Dec 1998
Ashman R B, Fulurija A, Papadimitriou J M
Abstract excerpt
The severity of systemic infection with the yeast Candida albicans has been shown to be under complex genetic control. C57/L mice carry an allele that is associated with an increase in tissue destruction when compared with C57Bl/6 mice; however, the gene affects only the severity of tissue lesion...
Topics
- Alleles
- Animals
- Brain Diseases
- Candida albicans
- Candidiasis
- Genes, Fungal
- Kidney Diseases
- Mice
- Mice, Inbred C57BL
- Sensitivity and Specificity