Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Minority resistant HIV-1 variants and the response to first-line NNRTI therapy.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2015

Nicot F, Sauné K, Raymond S, Jeanne N, Carcenac R, Lefebvre C, Cuzin L, Marchou B, Delobel P, Izopet J

Abstract excerpt

BACKGROUND: The presence of low-frequency HIV-1 variants with mutations making them resistant to non-nucleoside reverse-transcriptase inhibitors (NNRTI) could influence the virological response to first-line NNRTI therapy. OBJECTIVES: This study was designed to describe the proportions and quantities of NRTI and NNRTI-resistant variants in patients with successful first-line NNRTI therapy. STUDY DESIGN: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiretroviral Therapy, Highly Active
Share to CD4 Lymphocyte Count

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to HIV Infections

Share to Reverse Transcriptase Inhibitors

Share to RNA, Viral

Share to Viral Load

Source

Identifiers

PMID: 25542465
DOI: 10.1016/j.jcv.2014.10.020

Genes

GSS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Minority resistant HIV-1 variants and the response to first-line NNRTI therapy.PMID 25542465Read ↗

Minority variants associated with resistance to HIV-1 nonnucleoside reverse transcriptase inhibitors during primary infection.Semantic proximity Read ↗

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing.Semantic proximity Read ↗

Impact of Human Immunodeficiency Virus Type 1 Minority Variants on the Virus Response to a Rilpivirine-Based First-line Regimen.Semantic proximity Read ↗

Dynamics of HIV-1 quasispecies during antiviral treatment dissected using ultra-deep pyrosequencing.Semantic proximity Read ↗

Assessment of Transmitted HIV-1 Drug Resistance Mutations Using Ultra- Deep Pyrosequencing in a Turkish Cohort.Semantic proximity Read ↗

Ultra-deep sequencing of HIV-1 reverse transcriptase before start of an NNRTI-based regimen in treatment-naive patients.Semantic proximity Read ↗

Next-generation sequencing reveals major and minority HIV-1 drug resistance mutations in treatment-experienced individuals with virological failure.Semantic proximity Read ↗

Primary HIV-1 Drug Resistant Minority Variants.Semantic proximity Read ↗

Highly frequent HIV-1 minority resistant variants at baseline of the ANRS 139 TRIO trial had a limited impact on virological response.Semantic proximity Read ↗

Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.Semantic proximity Read ↗

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.Semantic proximity Read ↗

Low-abundance resistant mutations in HIV-1 subtype C antiretroviral therapy-naive individuals as revealed by pyrosequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.