Article
Enhanced microglial activity in FAAH(-/-) animals.
Life sciences - 1 Oct 2015
Ativie F, Albayram O, Bach K, Pradier B, Zimmer A, Bilkei-Gorzo A
Abstract excerpt
AIMS: Several lines of evidence suggest that the endocannabinoid system is involved in the regulation of glial activity. Enhanced levels of the endocannabinoid N-arachidonoyl ethanolamine (AEA, also referred to as anandamide) as well as non-cannabinoid lipids like palmitoylethanolamine (PEA) due to genetic deletion or pharmacologic blockade of its degrading enzyme fatty acid amide hydrolase (FAAH) reduced...
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