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Article

Specific microglial phagocytic phenotype and decrease of lipid oxidation in white matter areas during aging: Implications of different microenvironments.

Neurobiology of aging - 1 Sept 2021

Sanchez-Molina Paula, Almolda Beatriz, Benseny-Cases Núria, González Berta, Perálvarez-Marín Alex, Castellano Bernardo

Abstract excerpt

Physiological aging is characterized by an imbalance of pro-inflammatory and anti-inflammatory mediators leading to neuroinflammation. Microglial cells, which are highly regulated by the local microenvironment, undergo specific changes depending upon the brain area during aging. The aim of this study was to evaluate the influence of age over microglial cells along different brain areas and microenvironments. For...

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Identifiers

PMID: 34139605
DOI: 10.1016/j.neurobiolaging.2021.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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