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Beyond Symptom Management: FAAH Inhibition as a Path to Mitigate Alzheimer’s Disease Progression in Mouse Models of Amyloidosis

2024-07-23

Abstract excerpt

The endocannabinoid N -arachidonoylethanolamine (AEA) is a pro-homeostatic bioactive lipid known for its anti-inflammatory, anti-oxidative, immunomodulatory, and neuroprotective properties, which may contrast/mitigate Alzheimer’s disease (AD) pathology. This study explores the therapeutic potential of targeting fatty acid amide hydrolase (FAAH), the major enzyme degrading AEA, in mouse models of amyloidosis APP/P...

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Literature Corpus work
da32436f-7eac-5f3b-85a0-aa13a9965cd4
DOI
10.1101/2024.07.23.604774
Open publication

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Beyond Symptom Management: FAAH Inhibition as a Path to Mitigate Alzheimer’s Disease Progression in Mouse Models of AmyloidosisDOI 10.1101/2024.07.23.604774
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