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Article

Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice.

Neurobiology of disease - 1 May 2021

Maupu Clémence, Enderlin Julie, Igert Alexandre, Oger Myriam, Auvin Stéphane, Hassan-Abdi Rahma, Soussi-Yanicostas Nadia, Brazzolotto Xavier, Nachon Florian, Dal Bo Grégory, Dupuis Nina

Abstract excerpt

Organophosphate pesticides and nerve agents (OPs), are characterized by cholinesterase inhibition. In addition to severe peripheral symptoms, high doses of OPs can lead to seizures and status epilepticus (SE). Long lasting seizure activity and subsequent neurodegeneration promote neuroinflammation leading to profound pathological alterations of the brain. The aim of this study was to characterize...

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PMID: 33529768
DOI: 10.1016/j.nbd.2021.105276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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