Article
Microglia in the aging brain.
Journal of neuropathology and experimental neurology - 1 Mar 2006
Conde Jessica R, Streit Wolfgang J
Abstract excerpt
The aging brain is characterized by a demonstrable decrease in weight and volume, particularly after the age of 50. This atrophy, which affects both grey and white matter, is presumed to result from a loss of neurons and myelinated axons. Glial cells, on the other hand, appear to increase in the aging brain, which exhibits greater immunoreactivity with both astrocytic and microglial markers. This review is...
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