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Article

Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that is distinct from other autoimmune diseases.

Genes and immunity - 1 Mar 2015

Nititham J, Taylor K E, Gupta R, Chen H, Ahn R, Liu J, Seielstad M, Ma A, Bowcock A M, Criswell L A, Stahle M, Liao W

Abstract excerpt

Tumor necrosis factor alpha-inducible protein 3 (TNFAIP3) encodes a ubiquitin-modifying protein, A20, that is a critical regulator of inflammatory responses. TNFAIP3 polymorphisms are associated with the susceptibility to multiple autoimmune diseases (AIDs) including psoriasis, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis and celiac disease. In order to refine the TNFAIP3 association...

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Source

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Identifiers

PMID: 25521225
DOI: 10.1038/gene.2014.75
PMCID: PMC4526682

Genes

TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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