Article
Sequencing-based approach identified three new susceptibility loci for psoriasis.
Nature communications - 9 Jul 2014
Sheng Yujun, Jin Xin, Xu Jinhua, Gao Jinping, Du Xiaoqing, Duan Dawei, Li Bing, Zhao Jinhua, Zhan Wenying, Tang Huayang, Tang Xianfa, Li Yang, Cheng Hui, Zuo Xianbo, Mei Junpu, Zhou Fusheng, Liang Bo, Chen Gang, Shen Changbing, Cui Hongzhou, Zhang Xiaoguang, Zhang Change, Wang Wenjun, Zheng Xiaodong, Fan Xing, Wang Zaixing, Xiao Fengli, Cui Yong, Li Yingrui, Wang Jun, Yang Sen, Xu Lei, Sun Liangdan, Zhang Xuejun
Abstract excerpt
In a previous large-scale exome sequencing analysis for psoriasis, we discovered seven common and low-frequency missense variants within six genes with genome-wide significance. Here we describe an in-depth analysis of noncoding variants based on sequencing data (10,727 cases and 10,582 controls) with replication in an independent cohort of Han Chinese individuals consisting of 4,480 cases and 6,521 controls to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.