Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated analyses of DNA methylation and hydroxymethylation reveal tumor suppressive roles of ECM1, ATF5, and EOMES in human hepatocellular carcinoma.

Genome biology - 3 Dec 2014

Gao Fei, Xia Yudong, Wang Junwen, Lin Zhilong, Ou Ying, Liu Xing, Liu Weilong, Zhou Boping, Luo Huijuan, Zhou Baojin, Wen Bo, Zhang Xiuqing, Huang Jian

Abstract excerpt

BACKGROUND: Differences in 5-hydroxymethylcytosine, 5hmC, distributions may complicate previous observations of abnormal cytosine methylation statuses that are used for the identification of new tumor suppressor gene candidates that are relevant to human hepatocarcinogenesis. The simultaneous det...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methylcytosine
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Cytosine

Share to Epigenesis, Genetic

Share to Extracellular Matrix Proteins

Share to Liver Neoplasms

Share to T-Box Domain Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25517360
DOI: 10.1186/s13059-014-0533-9
PMCID: PMC4253612

Genes

ATF5
ECM1
EOMES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25517360-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated analyses of DNA methylation and hydroxymethylation reveal tumor suppressive roles of ECM1, ATF5, and EOMES in human hepatocellular carcinoma.PMID 25517360Read ↗

Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liverSemantic proximity Read ↗

Global DNA methylomes reveal oncogenic-associated 5-hydroxylmethylated cytosine (5hmC) signatures in the cell-free DNA of cancer patientsSemantic proximity Read ↗

Tissue-specific 5-hydroxymethylcytosine landscape of the human genomeSemantic proximity Read ↗

New guidelines for DNA methylome studies regarding 5-hydroxymethylcytosine for understanding transcriptional regulationSemantic proximity Read ↗

Tissue-specific 5-hydroxymethylcytosine landscape of the human genome.Semantic proximity Read ↗

Locus-specific enrichment analysis of 5-hydroxymethylcytosine reveals novel genes associated with breast carcinogenesisSemantic proximity Read ↗

Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers.Semantic proximity Read ↗

Identification of Methylation-Regulated Differentially Expressed Genes and Related Pathways in Hepatocellular Carcinoma: A Study Based on TCGA Database and Bioinformatics AnalysisSemantic proximity Read ↗

Genome-wide copy number analyses identified novel cancer genes in hepatocellular carcinoma.Semantic proximity Read ↗

Identification of Key Hydroxymethylated Genes and Transcription Factors Associated with Alpha-Fetoprotein-Negative Hepatocellular CarcinomaSemantic proximity Read ↗

Expression patterns of m <sup>6</sup> A RNA methylation regulators under apoptotic conditions in various human cancer cell linesSemantic proximity Read ↗

DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.