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Article

Rac1 modulates cardiomyocyte adhesion during mouse embryonic development.

Biochemical and biophysical research communications - 24 Jan 2015

Abu-Issa Radwan

Abstract excerpt

Rac1, a member of the Rho subfamily of small GTPases, is involved in morphogenesis and differentiation of many cell types. Here we define a role of Rac1 in cardiac development by specifically deleting Rac1 in the pre-cardiac mesoderm using the Nkx2.5-Cre transgenic driver line. Rac1-conditional knockout embryos initiate heart development normally until embryonic day 11.5 (E11.5); their cardiac mesoderm is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25514037
DOI: 10.1016/j.bbrc.2014.12.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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