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Article

Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium.

Cardiovascular research - 1 Oct 2014

Boczonadi Veronika, Gillespie Rachel, Keenan Iain, Ramsbottom Simon A, Donald-Wilson Charlotte, Al Nazer Mariana, Humbert Patrick, Schwarz Robert J, Chaudhry Bill, Henderson Deborah J

Abstract excerpt

AIMS: The organization and maturation of ventricular cardiomyocytes from the embryonic to the adult form is crucial for normal cardiac function. We have shown that a polarity protein, Scrib, may be involved in regulating the early stages of this process. Our goal was to establish whether Scrib plays a cell autonomous role in the ventricular myocardium, and whether this involves well-known polarity pathways....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Septal Defects, Ventricular

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Source

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Identifiers

PMID: 25139745
DOI: 10.1093/cvr/cvu193
PMCID: PMC4174891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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