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Article

A dual role of the GTPase Rac in cardiac differentiation of stem cells.

Molecular biology of the cell - 1 Jul 2003

Pucéat Michel, Travo Pierre, Quinn Mark T, Fort Philipe

Abstract excerpt

The function of the GTPase Rac1, a molecular switch transducing intracellular signals from growth factors, in differentiation of a specific cell type during early embryogenesis has not been investigated. To address the question, we used embryonic stem (ES) cells differentiated into cardiomyocytes, a model that faithfully recapitulates early stages of cardiogenesis. Overexpression in ES cells of a constitutively...

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Identifiers

PMID: 12857864
DOI: 10.1091/mbc.e02-09-0562
PMCID: PMC165676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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