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Article

The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis.

Developmental biology - 15 May 2014

Dickover Michael, Hegarty Jeffrey M, Ly Kim, Lopez Diana, Yang Hongbo, Zhang Ruilin, Tedeschi Neil, Hsiai Tzung K, Chi Neil C

Abstract excerpt

The vertebrate heart undergoes early complex morphologic events in order to develop key cardiac structures that regulate its overall function (Fahed et al., 2013). Although many genetic factors that participate in patterning the heart have been elucidated (Tu and Chi, 2012), the cellular events that drive cardiac morphogenesis have been less clear. From a chemical genetic screen to identify cellular pathways that...

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Identifiers

PMID: 24607366
DOI: 10.1016/j.ydbio.2014.02.014
PMCID: PMC4101123

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