Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rho Kinases in Embryonic Development and Stem Cell Research

19 Jan 2022

Abstract excerpt

The Rho-associated coiled-coil containing kinases (ROCKs or Rho kinases) belong to the AGC (PKA/PKG/PKC) family of serine/threonine kinases and are major downstream effectors of small GTPase RhoA, a key regulator of actin-cytoskeleton reorganization. The ROCK family contains two members, ROCK1 and ROCK2, which share 65% overall identity and 92% identity in kinase domain. ROCK1 and ROCK2 were assumed to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Microtubule and mitosis dynamics
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35043239
DOI: 10.1007/s00005-022-00642-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rho Kinases in Embryonic Development and Stem Cell ResearchPMID 35043239Read ↗

Rho Kinases in Health and Disease: From Basic Science to Translational Research.Semantic proximity Read ↗

Rocking the Boat: The Decisive Roles of Rho Kinases During Oocyte, Blastocyst, and Stem Cell DevelopmentSemantic proximity Read ↗

Targeting ROCK signaling in health, malignant and non-malignant diseases.Semantic proximity Read ↗

Novel Insights into the Roles of Rho Kinase in Cancer.Semantic proximity Read ↗

Rho signaling research: history, current status and future directionsSemantic proximity Read ↗

Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signalingSemantic proximity Read ↗

Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9Semantic proximity Read ↗

Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II.Semantic proximity Read ↗

Targeting Rho GTPase Signaling Networks in CancerSemantic proximity Read ↗

Rho-Associated Kinase Activity Is Required for Proper Morphogenesis of the Inner Cell Mass in the Mouse Blastocyst1Semantic proximity Read ↗

ROCK1 is associated with non-syndromic cleft palate.Semantic proximity Read ↗

Role of Rho GTPases in stem cell regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.