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Article

Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma.

Cancer letters - 28 Feb 2015

Fung Christopher, Zhou Pei, Joyce Sonali, Trent Kerry, Yuan Jian-Min, Grandis Jennifer R, Weissfeld Joel L, Romkes Marjorie, Weeks Daniel E, Egloff Ann Marie

Abstract excerpt

EGFR polymorphisms have not been thoroughly evaluated for association with head and neck squamous cell carcinoma (HNSCC) risk. We genotyped 578 HNSCC patients and 588 cancer-free controls for 60 EGFR single nucleotide polymorphisms (SNPs) and tested associations with HNSCC risk. EGFR intronic SNPs rs12535536, rs2075110, rs1253871, rs845561 and rs6970262 and synonymous SNP were associated with HNSCC risk...

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Source

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Identifiers

PMID: 25511740
DOI: 10.1016/j.canlet.2014.12.008
PMCID: PMC4295492

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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