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Article

Impact of genetic variants in clinical outcome of a cohort of patients with oropharyngeal squamous cell carcinoma.

Scientific reports - 19 Jun 2020

de Carvalho Ana Carolina, Perdomo Sandra, Dos Santos Wellington, Fernandes Gabriela Carvalho, de Jesus Lais Machado, Carvalho Raiany Santos, Scapulatempo-Neto Cristovam, de Almeida Gisele Caravina, Sorroche Bruna Pereira, Arantes Lidia Maria Rebolho Batista, Melendez Matias Eliseo, De Marchi Pedro, Hayes Neil, Reis Rui Manuel, Carvalho André Lopes

Abstract excerpt

Tobacco- or human papillomavirus- driven oropharyngeal squamous cell carcinomas (OpSCC) represent distinct clinical, biological and epidemiological entities. The aim of this study was to identify genetic variants based on somatic alterations in OpSCC samples from an admixed population, and to test for association with clinical features. The entire coding region of 15 OpSCC driver genes was sequenced by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

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Source

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Identifiers

PMID: 32561788
DOI: 10.1038/s41598-020-66741-z
PMCID: PMC7305218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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