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Article

Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.

PloS one - 1 Jan 2012

Yu Hongping, Liu Zhensheng, Huang Yu-Jing, Yin Ming, Wang Li-E, Wei Qingyi

Abstract excerpt

BACKGROUND: Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important role in nucleotide excision repair and participates in removal of DNA interstrand cross-links and DNA double-strand breaks. Single nucleotide polymorphisms (SNPs) in ERCC4 may impact repair capacity and affect cancer susceptibility. METHODOLOGY/PRINCIPAL FINDINGS: In this case-control study, we evaluated associations of...

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Identifiers

PMID: 22848636
DOI: 10.1371/journal.pone.0041853
PMCID: PMC3407112

Genes

ERCC4

Provenance

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