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Article

Epidermal growth factor receptor (EGFR) mutations as biomarker for head and neck squamous cell carcinomas (HNSCC).

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 May 2014

Nagalakshmi K, Jamil Kaiser, Pingali Usharani, Reddy M Vishnuvardhan, Attili Suresh S V

Abstract excerpt

CONTEXT: Mutations in tyrosine kinase domain (TK) of epidermal growth factor receptor (EGFR) lead to signalling interruptions in several cancers. OBJECTIVE: To understand EGFR mutations in head and neck squamous cell carcinomas (HNSCC), and their role as biomarkers. METHODS: Screened 129 HNSCC patients and 150 controls for mutations in the TK domain using polymerase chain reaction (PCR), single strand...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24712396
DOI: 10.3109/1354750X.2014.895852

Genes

EGFR

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