Article
Gene-environment interactions of novel variants associated with head and neck cancer.
Head & neck - 1 Aug 2012
Liang Caihua, Marsit Carmen J, Houseman E Andres, Butler Rondi, Nelson Heather H, McClean Michael D, Kelsey Karl T
Abstract excerpt
BACKGROUND: A genome-wide association study for upper aerodigestive tract cancers identified 19 candidate single-nucleotide polymorphisms (SNPs). We used these SNPs to investigate the potential gene-gene and gene-environment interactions in head and neck squamous cell carcinoma (HNSCC) risk. METHODS: The 19 variants were genotyped using Taqman assays among 575 cases and 676 controls in our population-based...
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