Article
Vascular function of the mesenteric artery isolated from thyroid hormone receptor-α knockout mice.
Journal of vascular research - 1 Jan 2014
Liu Kiao Ling, Lo Ming, Canaple Laurence, Gauthier Karine, Del Carmine Peggy, Beylot Michel
Abstract excerpt
OBJECTIVE: This study evaluated the consequences of thyroid hormone receptor-α (TRα) disruption on vascular reactivity. METHODS: The activity of superior mesenteric arteries isolated from TRα knockout mice generated in the SV129 background (TRα(0/0)SV) or in a pure C57BL/6 background (TRα(0/0)C57) was compared to that of their corresponding wild-type strains (SV129 or C57BL/6 mice). RESULTS: The wild-type SV129...
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