Preliminary characterization of cis interactions between mutations of poliovirus genome.

doi:10.1016/s0923-2516(89)80110-4

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Article

Preliminary characterization of cis interactions between mutations of poliovirus genome.

Research in virology - 1 Jan 2000

Agut H, Kean K M, Fichot O, Girard M

Abstract excerpt

The effects of three distinct point mutations in the P3 genomic region of poliovirus type 1 (Mahoney strain) have previously been analysed. A U to C change at position 5658, which modifies the proteinase 3C, is responsible for a small plaque phenotype and defective RNA replication. An A to G chan...

Topics

DNA-Directed RNA Polymerases
Genes, Viral
Mutation
Phenotype
Poliovirus

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