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Article

Functional and genetic plasticities of the poliovirus genome: quasi-infectious RNAs modified in the 5'-untranslated region yield a variety of pseudorevertants.

Journal of virology - 1 Oct 1993

Gmyl A P, Pilipenko E V, Maslova S V, Belov G A, Agol V I

Abstract excerpt

Poliovirus RNA species with nucleotides 564 to 571 deleted or with a secondary structure domain (positions 564 to 629) replaced by a shorter irregular oligonucleotide have been engineered previously; these RNAs have been considered quasi-infectious (yielding a single late revertant plaque) and dead, respectively (E. Pilipenko, A. Gmyl, Y. Svitkin, S. Maslova, A. Sinyakov, and V. Agol, Cell 68:119-131, 1992). By...

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Identifiers

PMID: 8396686
DOI: 10.1128/JVI.67.10.6309-6316.1993
PMCID: PMC238059

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