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Article

Genetic stability of poliovirus insertion mutants with a foreign oligopeptide on the capsid surface.

Research in virology - 1 Jan 2000

Christodoulou C, Pelletier I, Colbère-Garapin F

Abstract excerpt

The genetic stability of poliovirus mutants which carry a foreign oligopeptide on the surface of their capsid was studied (1) upon mutant isolation, (2) after serially diluted passages in cell cultures, and (3) in persistently infected cultures which have been recently developed. Viruses having a 3-codon insertion within the VP1 capsid protein-encoding region appeared to be extremely stable, except in the...

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PMID: 2559441
DOI: 10.1016/s0923-2516(89)80137-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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