Genetic stability of poliovirus insertion mutants with a foreign oligopeptide on the capsid surface.

doi:10.1016/s0923-2516(89)80137-2

Back to search

Article

Genetic stability of poliovirus insertion mutants with a foreign oligopeptide on the capsid surface.

Research in virology - 1 Jan 2000

Christodoulou C, Pelletier I, Colbère-Garapin F

Abstract excerpt

The genetic stability of poliovirus mutants which carry a foreign oligopeptide on the surface of their capsid was studied (1) upon mutant isolation, (2) after serially diluted passages in cell cultures, and (3) in persistently infected cultures which have been recently developed. Viruses having a...

Topics

Animals
Base Sequence
Capsid
Codon
DNA Transposable Elements
DNA, Viral
Humans
Molecular Sequence Data
Mutation
Neuroblastoma
Plasmids
Poliovirus
RNA, Viral
Transfection
Tumor Cells, Cultured
Vero Cells

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.