Genetic stability and instability of the cis-acting control element of the 5' untranslated region of the poliovirus RNA.

Article

Genetic stability and instability of the cis-acting control element of the 5' untranslated region of the poliovirus RNA.

Developments in biological standardization - 1 Jan 1993

Agol V I

Abstract excerpt

The poliovirus genome exhibits tremendous plasticity, which is particularly evident when mutations diminishing the growth potential are introduced into the genome. An amazing variability can be observed even among the genomes derived from a single plaque. Not less amazing is the stability of the...

Topics

Base Sequence
Mutation
Phenotype
Poliovirus
Poliovirus Vaccine, Oral
RNA, Viral
Viral Proteins
Virulence
Virus Replication

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