Article
Genetic stability and instability of the cis-acting control element of the 5' untranslated region of the poliovirus RNA.
Developments in biological standardization - 1 Jan 1993
Agol V I
Abstract excerpt
The poliovirus genome exhibits tremendous plasticity, which is particularly evident when mutations diminishing the growth potential are introduced into the genome. An amazing variability can be observed even among the genomes derived from a single plaque. Not less amazing is the stability of the viral RNA sequences, which could be revealed, for example, upon the analysis of populations of a given viral strain...
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