Article
Association between NME8 locus polymorphism and cognitive decline, cerebrospinal fluid and neuroimaging biomarkers in Alzheimer's disease.
PloS one - 1 Jan 2014
Liu Ying, Yu Jin-Tai, Wang Hui-Fu, Hao Xiao-Ke, Yang Yu-Fen, Jiang Teng, Zhu Xi-Chen, Cao Lei, Zhang Dao-Qiang, Tan Lan
Abstract excerpt
Recently, a large meta-analysis of five genome wide association studies (GWAS) identified a novel locus (rs2718058) adjacent to NME8 that played a preventive role in Alzheimer's disease (AD). However, this link between the single nucleotide polymorphism (SNP) rs2718058 and the pathology of AD have not been mentioned yet. Therefore, this study assessed the strength of association between the NME8 rs2718058...
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