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Article

APOE genotype and neuroimaging markers of Alzheimer's disease: systematic review and meta-analysis.

Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2015

Liu Ying, Yu Jin-Tai, Wang Hui-Fu, Han Pei-Ran, Tan Chen-Chen, Wang Chong, Meng Xiang-Fei, Risacher Shannon L, Saykin Andrew J, Tan Lan

Abstract excerpt

OBJECTIVE: We aimed to examine the association of apolipoprotein E (APOE) ɛ4 genotype with neuroimaging markers of Alzheimer's disease: hippocampal volume, brain amyloid deposition and cerebral metabolism. METHODS: We performed a systematic review and meta-analysis of 14 cross-sectional studies identified in Pubmed from 1996 to 2014 (n=1628). The pooled standard mean difference (SMD) was used to estimate the...

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Source

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Identifiers

PMID: 24838911
DOI: 10.1136/jnnp-2014-307719
PMCID: PMC4331076

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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