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Article

Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 May 2018

Chung Jaeyoon, Wang Xulong, Maruyama Toru, Ma Yiyi, Zhang Xiaoling, Mez Jesse, Sherva Richard, Takeyama Haruko, Lunetta Kathryn L, Farrer Lindsay A, Jun Gyungah R

Abstract excerpt

INTRODUCTION: Genetic associations for endophenotypes of Alzheimer's disease (AD) in cognitive stages preceding AD have not been thoroughly evaluated. METHODS: We conducted genome-wide association studies for AD-related endophenotypes including hippocampal volume, logical memory scores, and cerebrospinal fluid Aβ42 and total/phosphorylated tau in cognitively normal (CN), mild cognitive impairment, and AD dementia...

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Identifiers

PMID: 29274321
DOI: 10.1016/j.jalz.2017.11.006
PMCID: PMC5938137

Genes

MTUS1
SRRM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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