Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Effects of PICALM rs3851179 and Age on Brain Atrophy and Cognition Along the Alzheimer's Disease Continuum.

Molecular neurobiology - 1 Sept 2024

Wu Zhiwei, Chen Jinhong, Liu Yuanqing, Yang Yiwen, Feng Mengmeng, Dai Hui

Abstract excerpt

Rs3851179, a variant of PICALM gene, and age are the risk factors of Alzheimer's disease (AD). AD is divided into early-onset AD (EOAD, < 65 years) and late-onset AD (LOAD, ≥ 65 years) by age. The purpose was to investigate the impact of different genotypes of PICALM rs3851179 on brain atrophy and cognitive decline across the AD continuum in different age groups. Four hundred seven cognitive normal (CN) controls,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Atrophy

Share to Cognition

Share to Cognitive Dysfunction

Share to Magnetic Resonance Imaging

Share to Monomeric Clathrin Assembly Proteins

Source

Identifiers

PMID: 38363532
DOI: 10.1007/s12035-024-03953-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Effects of PICALM rs3851179 and Age on Brain Atrophy and Cognition Along the Alzheimer's Disease Continuum.PMID 38363532Read ↗

Association of Alzheimer's disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration.Semantic proximity Read ↗

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease.Semantic proximity Read ↗

Correlation of PICALM polymorphism rs3851179 with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review.Semantic proximity Read ↗

PICALM rs3851179 Variant Confers Susceptibility to Alzheimer's Disease in Chinese Population.Semantic proximity Read ↗

The Interactive Effects of Age and PICALM rs541458 Polymorphism on Cognitive Performance, Brain Structure, and Function in Non-demented Elderly.Semantic proximity Read ↗

Impact of PICALM and CLU on hippocampal degeneration.Semantic proximity Read ↗

The Impact of UNC5C Genetic Variations on Neuroimaging in Alzheimer's Disease.Semantic proximity Read ↗

rs3851179G>A in PICALM is Protective Against Alzheimer's Disease in Five Different Countries Surrounding the Mediterranean.Semantic proximity Read ↗

PICALM gene rs3851179 polymorphism contributes to Alzheimer's disease in an Asian population.Semantic proximity Read ↗

Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese.Semantic proximity Read ↗

Impacts of PICALM and CLU variants associated with Alzheimer's disease on the functional connectivity of the hippocampus in healthy young adults.Semantic proximity Read ↗

Association between NME8 locus polymorphism and cognitive decline, cerebrospinal fluid and neuroimaging biomarkers in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.