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Article

A genome-wide association study of longitudinal change in CSF tau among non-demented elderly.

Bratislavske lekarske listy - 1 Jan 2024

Liu Yingbei, Zhang Na, Liu Shulei, Zhong Xiaoling, Wang Ling

Abstract excerpt

METHODS: This study conducted a genome-wide association study (GWAS) on longitudinal CSF t-tau and genotype data from 319 non-Hispanic Caucasians within the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. The aim was to identify genetic determinants influencing the rate of change in CSF t-tau, a key biomarker in AD. RESULTS: The GWAS identified a significant single nucleotide polymorphism (SNP),...

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PMID: 39344768
DOI: 10.4149/BLL_2024_99

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