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Article

Joint effects of genetic variants in multiple loci on the risk of coronary artery disease in Chinese Han subjects.

Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2012

Lv Xiaofei, Zhang Yuan, Rao Shaoqi, Qiu Jian, Wang Min, Luo Xiaoqin, Zuo Xiaoyu, Su Dongfang, Feng Xiang, Yang Yan, Ouyang Ping, Chen Yibing, Li Xinrui, Xiao Yunjun, Ling Wenhua

Abstract excerpt

BACKGROUND: The aim of the present study was to explore risk variants for coronary artery disease (CAD) and to evaluate their joint effects (quantified by genetic risk score; GRS) on the discrimination of CAD in a Chinese Han sample. METHODS AND RESULTS: An association analysis of 91 single nucleotide polymorphisms (SNPs) with CAD risk was undertaken in 1,007 CAD patients and 889 healthy controls. Two GRSs,...

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PMID: 22664640
DOI: 10.1253/circj.cj-12-0156

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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