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Article

Assessment of the value of a genetic risk score in improving the estimation of coronary risk.

Atherosclerosis - 1 Jun 2012

Lluis-Ganella Carla, Subirana Isaac, Lucas Gavin, Tomás Marta, Muñoz Daniel, Sentí Mariano, Salas Eduardo, Sala Joan, Ramos Rafel, Ordovas Jose M, Marrugat Jaume, Elosua Roberto

Abstract excerpt

BACKGROUND: The American Heart Association has established criteria for the evaluation of novel markers of cardiovascular risk. In accordance with these criteria, we assessed the association between a multi-locus genetic risk score (GRS) and incident coronary heart disease (CHD), and evaluated whether this GRS improves the predictive capacity of the Framingham risk function. METHODS AND RESULTS: Using eight...

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Identifiers

PMID: 22521901
DOI: 10.1016/j.atherosclerosis.2012.03.024
PMCID: PMC3697002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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