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Article

GBA-associated Parkinson's disease: reduced survival and more rapid progression in a prospective longitudinal study.

Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2015

Brockmann Kathrin, Srulijes Karin, Pflederer Sylvia, Hauser Ann-Kathrin, Schulte Claudia, Maetzler Walter, Gasser Thomas, Berg Daniela

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) patients with GBA mutations show an earlier age at onset and more severe non-motor symptoms compared with PD patients without GBA mutations. OBJECTIVE: This study was undertaken to evaluate progression of motor and non-motor symptoms in sporadic PD patients depending on the mutational GBA status. METHODS: We used regression analysis to evaluate independent effects of the...

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Identifiers

PMID: 25448271
DOI: 10.1002/mds.26071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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