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Article

Survival and dementia in GBA-associated Parkinson's disease: The mutation matters.

Annals of neurology - 1 Nov 2016

Cilia Roberto, Tunesi Sara, Marotta Giorgio, Cereda Emanuele, Siri Chiara, Tesei Silvana, Zecchinelli Anna L, Canesi Margherita, Mariani Claudio B, Meucci Nicoletta, Sacilotto Giorgio, Zini Michela, Barichella Michela, Magnani Corrado, Duga Stefano, Asselta Rosanna, Soldà Giulia, Seresini Agostino, Seia Manuela, Pezzoli Gianni, Goldwurm Stefano

Abstract excerpt

OBJECTIVE: The objective of this work was to investigate survival, dementia, and genotype-phenotype correlations in patients with Parkinson's disease (PD) with and without mutations on the glucocerebrosidase gene (GBA). METHODS: We included 2,764 unrelated consecutive PD patients: 123 GBA carriers (67 mild-p.N370S and 56 severe mainly p.L444P) and 2,641 noncarriers. Brain perfusion and dopamine transporter...

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Identifiers

PMID: 27632223
DOI: 10.1002/ana.24777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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