Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts.

Journal of Parkinson's disease - 1 Jan 2000

Maple-Grødem Jodi, Paul Kimberly C, Dalen Ingvild, Ngo Kathie J, Wong Darice, Macleod Angus D, Counsell Carl E, Bäckström David, Forsgren Lars, Tysnes Ole-Bjørn, Kusters Cynthia D J, Fogel Brent L, Bronstein Jeff M, Ritz Beate, Alves Guido

Abstract excerpt

BACKGROUND: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson's disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on lacking whether patients with GBA-associated PD differ in their risk of developing motor complications compared to the general PD population. OBJECTIVE: To evaluate the association of GBA carrier...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dyskinesias
Share to Glucosylceramidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Levodopa

Share to Mental Status and Dementia Tests

Share to Mutation

Share to Parkinson Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 34275908
DOI: 10.3233/JPD-212657
PMCID: PMC8609705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts.PMID 34275908Read ↗

GBA-associated PD: chances and obstacles for targeted treatment strategies.Semantic proximity Read ↗

Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease.Semantic proximity Read ↗

Features of GBA-associated Parkinson's disease at presentation in the UK Tracking Parkinson's study.Semantic proximity Read ↗

GBA-Related Parkinson's Disease: Dissection of Genotype-Phenotype Correlates in a Large Italian Cohort.Semantic proximity Read ↗

Impact of GBA1 variants on long-term clinical progression and mortality in incident Parkinson's disease.Semantic proximity Read ↗

Faster disease progression in Parkinson's disease with glucocerebrosidase genotype: But not apparent immediate from diagnosis.Semantic proximity Read ↗

A benign course of Parkinson's disease associated with different mutations in the glucocerebrosidase gene - A case series.Semantic proximity Read ↗

GBA-associated Parkinson's disease: reduced survival and more rapid progression in a prospective longitudinal study.Semantic proximity Read ↗

Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesiaSemantic proximity Read ↗

Association of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression.Semantic proximity Read ↗

Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease.Semantic proximity Read ↗

Early motor response to dopamine replacement therapy in Parkinson's disease patients carrying GBA variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.