Article
The V-val subtype Epstein-Barr virus nuclear antigen 1 promotes cell survival after serum withdrawal.
Oncology reports - 1 Feb 2015
Chao Mei, Wang Hsiao-Ning, Lu Yi Jin, Chang Yu-Sun, Yu Jau-Song
Abstract excerpt
Epstein-Barr virus (EBV) can establish latent infection and has been associated with various human cancers. Epstein-Barr nuclear antigen 1 (EBNA1) is the only viral protein that is expressed in all EBV-associated malignant tissues. The N- and C-terminal domains of EBNA1, which are connected by internal glycine/alanine-rich short repeat sequences of various sizes, show sequence divergence across EBV strains...
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