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Article

EBNA-1 sequence variations reflect active EBV replication and disease status or quiescent latency in lymphocytes.

Journal of medical virology - 1 Mar 2003

Wang Jiin-Tarng, Sheeng Tzung-Shiahn, Su Ih-Jen, Chen Jen-Yang, Chen Mei-Ru

Abstract excerpt

EBV infects most of the global population, but only a small percentage of infected individuals develop EBV-associated malignancies. Host and viral factors may play a role in determining the clinical outcome. Because EBNA-1 functions as an oriP binding protein and links the episomal viral DNA to metaphase chromosomes, variation of EBNA-1 has been suggested to contribute to determining the tissue tropism of EBV and...

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Identifiers

PMID: 12526054
DOI: 10.1002/jmv.10305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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