Article
Impact of EBV Essential Nuclear Protein EBNA-3C on B-Cell Proliferation and Apoptosis
1 Mar 2013
Abstract excerpt
For over 40 years, EBV infection has been implicated in the etiology of a variety of lymphoid malignancies with the exceptional ability to drive resting B cells to continuously proliferate by successfully overriding cellular apoptotic stimuli. EBV utilizes the normal physiology of B-cell differentiation to persist within the memory B-cell pool of the immunocompetent host and subsequently establishes a life-long...
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