Article
[Functions of V-val subtype of Epstein-Barr nuclear antigen 1].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Mar 2008
Mai Shi-Juan, Li Da-Jiang, Zhou Xin-Xi, Chen Li-Zhen, Feng Qi-Sheng, Zhang Ru-Hua, Yu Xing-Juan, Zeng Yi-Xin
Abstract excerpt
BACKGROUND & OBJECTIVE: Epstein-Barr viral nuclear antigen 1 (EBNA1) plays a crucial role in the latency of Epstein-Barr virus (EBV). A close relation of V-val subtype of EBNA1 with nasopharyngeal carcinoma (NPC) was suggested by its preference to infect NPC cells. This study was to investigate the functional difference between prototype and V-val EBNA1 in epithelial cell line HEK293. METHODS: The coding...
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