Article
The association of P-selectin glycoprotein ligand-1 VNTR polymorphisms with coronary stent restenosis.
Journal of thrombosis and thrombolysis - 1 Jun 2007
Ozben Beste, Diz-Kucukkaya Reyhan, Bilge Ahmet K, Hancer Veysel S, Oncul Aytac
Abstract excerpt
BACKGROUND: P-selectin and P-selectin glycoprotein ligand-1 (PSGL-1) regulate the initial interactions between leukocytes, activated platelets and endothelial cells. Recently, a variable number of tandem repeats (VNTR) polymorphism in PSGL-1 gene affecting the length of the extracellular domain of PSGL-1 and the distance of the P-selectin binding site to the cell surface has been described. There are limited...
Topics
- Aged
- Blood Group Antigens
- Coronary Artery Disease
- Coronary Restenosis
- Family Health
- Female
- Gene Frequency
- Genotype
- Humans
- Male
- Membrane Glycoproteins
