Article
The association of the Thr715Pro P-selectin genotype with levels of P-selectin in platelet concentrates.
Vox sanguinis - 1 Nov 2014
Jilma-Stohlawetz P, Mannhalter C, Kaider A, Waidacher T, Jilma B, Panzer S
Abstract excerpt
BACKGROUND AND OBJECTIVES: P-selectin is stored in the alpha granules of platelets and in the Weibel Palade bodies of endothelial cells; upon activation, it is translocated to the cell surface and released into the plasma in soluble form. One variant of the P-selectin gene, the Thr715Pro polymorp...
Topics
- Adult
- Blood Platelets
- Enzyme-Linked Immunosorbent Assay
- Female
- Genotype
- Heterozygote
- Humans
- Male
- Middle Aged
- P-Selectin
- Peptide Fragments
- Plateletpheresis
- Polymorphism, Single Nucleotide