Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

24 Nov 2014

Abstract excerpt

BACKGROUND: Interferon induced transmembrane proteins 1, 2 and 3 (IFITMs) belong to a family of highly related antiviral factors that have been shown to interfere with a large spectrum of viruses including Filoviruses, Coronaviruses, Influenza virus, Dengue virus and HIV-1. In all these cases, the reported mechanism of antiviral inhibition indicates that the pool of IFITM proteins present in target cells blocks...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to interferon and immune responses
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25422070
DOI: 10.1186/s12977-014-0103-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivityPMID 25422070Read ↗

Divergent HIV-1 Restriction Phenotypes of IFITMs Expressed in Target Cells and Incorporated into VirionsSemantic proximity Read ↗

Divergent HIV-1 Restriction Phenotypes of IFITMs Expressed in Target Cells and Incorporated into Virions.Semantic proximity Read ↗

More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteinsSemantic proximity Read ↗

IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunitySemantic proximity Read ↗

IFITM proteins inhibit HIV-1 protein synthesisSemantic proximity Read ↗

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral InfectionsSemantic proximity Read ↗

Antiviral Role of IFITM Proteins in African Swine Fever Virus InfectionSemantic proximity Read ↗

IFITM-Family Proteins: The Cell's First Line of Antiviral DefenseSemantic proximity Read ↗

Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction.Semantic proximity Read ↗

IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic EntrySemantic proximity Read ↗

A specific anti-IFITM2 antibody bars the way to SARS-CoV-2 entry into host cellsSemantic proximity Read ↗

Current Progress on Host Antiviral Factor IFITMsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.