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Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection

26 Apr 2016

Abstract excerpt

The interferon-induced transmembrane (IFITM) protein family is a group of antiviral restriction factors that impair flexibility and inhibit membrane fusion at the plasma or the endosomal membrane, restricting viral progression at entry. While IFITMs are widely known to inhibit several single-stranded RNA viruses, there are limited reports available regarding their effect in double-stranded DNA viruses. In this...

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PMID: 27116236
DOI: 10.1371/journal.pone.0154366

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