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Article

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral Infections

8 Jan 2019

Abstract excerpt

Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that localize in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into host cells by interrupting the membrane fusion between viral envelope and cellular membranes, but also reduce the production of infectious virions or infectivity of progeny virions. Not surprisingly, some viruses can evade the...

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Identifiers

PMID: 30687247
DOI: 10.3389/fmicb.2018.03228

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